Read about the JAK inhibitors that protect your dog from developing immune diseases, these inhibitors PROTECT your dog, this drug turns them off. Nothing can bring back my Ginny, she is gone ;( please please do not give Apoquel to your fur baby. He ended up in shock and went into V Tach and the cardiologist put him on a procainamide drip to stop the VT and stabilize him, which worked, but who knows for how long. During this time we went back to the vet for guidance and he was put on Prozac for dogs. Hello Dr I criticize but choose not to use my real name, This article is 100% based on FDA Veterinary ADE reports- you may want to visit the FDA site and read the stats for yourself. He had pancratitis attack 2 yrs ago, so they do not want to give him prednisone alot. We put my boy on it and yes, it did work great. We had a lovely dog who frequently got ear infections and because of this drug we have no dog. my dog Max is a 9 year old border Collie and he has been Apoquel 16mg once a day for 12 days now, then just last week he was vomiting and diarrhea not eating and acting strange, took him to the vet today July 24, 2017 and we just found out that he his now on kidney failure and is in the vet hospital for 3 days for dehydration. That was a year ago. It has been the Apoquel doing all of this, I believe. If you are into animal welfare, you probably should stay away from those supplements. but she started having side effects, excessive thirst, frequent urination, barely made it out the door. I wouldnt recommend it after our issues with it and reading others comments. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Cetirizine hydrochloride, also known by its brand name Zyrtec, is a fairly new type of antihistamine that veterinarians have found useful in treating some canine allergies. Apoquel is a medication that works at the skin level to reduce the mechanism that causes itch. It is dangerous. Metronidazole can have a bitter flavor and so may be best tolerated when given with food. The omega 3 dose I suggest is 1000 mg per 10lbs daily- this works out to giving 1 tablespoon of flax per 50lbs daily to your dog. I think it could be a very dangerous drug. It may be used off label to treat skin infections in cats and urinary tract infections in dogs. I ended up at the emergency hospital where he was put on antibiotics, IVs and had X-rays, bloods and ultrasounds done. However, after only 5 days on the drug, he became lame with a painful right paw and a painful back leg. He refused to eat or drink water for hours. As luck would have it, I did a research on both meds as I normally do with any meds, and as fate would have it came upon this site. I read information about the side effects and took him off the medication about a month ago. When we moved my new vet recommended the new drug that was having great results on allergies in dogs Apoquel. Zoetis, Apoquel's manufacturer, conducted a long-term (two year) study examining 247 dogs and the side effects of Apoquel they experienced. Please do not give your dog this medicine I know it makes him stop itching but the outcome is not worth it putting him to sleep, its like putting your child asleep. The meds worked for 3 days of clearing his itching and swollen eyes but then the vomiting, not eating, stomach pains, panting, not drinking, exhaustion, completely out of it wondering and hiding in corners, didnt open his eyes for 3 days, and death happened. of the development of severe pyoderma (after day 19) and one dog withdrew because of the Also she was not falling down for no reason. She was burping, licking her mouth, eating grass and her breath smelt very bad. If Zoetis produces the vaccines that were usedwell that would truly answer a lot of questions. This is the method to protect the public from unknown side effects that only appear when thousands of patients are exposed to the medication. You wouldnt Inject AIDS in your child, that is what this stuff sounds like. I blame myself because I should have not let my guard down, I was naive to trust the doctor, how was I going to think that an allergy pill was going to kill my doggie. (Answered 2023), What Are Cat and Dog Paws Adapted for? She has been on it for about 3 weeks now. Our Angel was on prednisone for quite awhile. Every dog is different, so you have to try different foods; there is not just ONE right food. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Dogsnet is a participant in the Amazon EU Associates Programme, an affiliate advertising programme designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.co.uk Dogsnet is also a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. We have a coon hound with skin allergies. Over the last six years he has been on Benadryl, Prednisone and other anti-fungal drugs. Hamish is very threadbare and I have been loathed to clip him. For a sonogram and X-rays that showed everything is normal. Still sweet and wants to play but, can hardly find the ball when it is right in front of her face. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. He had never had a seizure in his life and had never behaved that way. Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. While still within reference ranges, mean serum globulin and mean white blood cell, Wow my eyes are wide. However, after about a month and a half our four year old dog started vomiting and was extremely lethargic. I certainly cant say for sure that the Apoquel caused this tumor but am quite confident that it probably exacerbated it. Vet suggested Apoquel. We just make sure to take him out frequently to be safe. Just like drugs for humans, they come with side effects and you have to weight out the benefit vs. the risks. This medicine stopped the itch and it had wonderful results UNTIL recently she had 2 seizures!!!! Thanks to all for yoru comments. company and they said no connections. Bloods came back as normal and vet said it wasnt the Apoquel that caused the fits. Thank you all for sharing. But it is not the only antihistamine that vets use. Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. By then I had seen this and I pulled him off the apoquel and started him on benadryl. My chocolate lab has been on Apoquel for years now. One has had a spot on her left leg that she keeps licking and biting for 2 years. I will need to confine her if she continues to pee everywhere. Fuck this drug. Hello, I have 2 german shepherds. My 11 year old shih tzu has really terrible allergies once we moved from a large city to the suburbs he went downhill with allergies, it literally only took 4 hours before he started oozing green from his eyes. My Vet said it looked cancerous when she aspirated it, does not mean that it is malignant but she did sound somewhat worried and talked about the way the nuclei looked under the microscope. I think a class action suit against the makers of apparel is called for. One morning about 5AM she woke me standing up on the bed and she froze and fell off the bed like a statue and had a seizure. Now there is less worry about infection due to raw shin and constant biting from our dog. Is APOQUEL Its quite disturbing that those of us who have had a negative experience with Apoquel end up with our posts buried deep beneath a mountain of Ads that proclaim it as a wonder drug. It took about 3 months for her red blood cells to start reproducing and return to normal. We did zyrtec lorantidine vistari She gave him different food and Hydroxizine, along with antinausea pills. Among dogs in the oclacitinib group, one dog withdrew from the study because Today we was at the vets, my Westie mix bison was given Apoquel 5.6grm and I gave him one today,after reading all your comments. Vet said to try him on Apoquel. My 6 year old french bull dog was put on Apoquel on 17/3/17 he had his first seizure on 2/4/17 he passed away on 4/4/17 my dog was fit and healthy up till his first seizure. I guess I need to do some more research. I cant wait to see what the blood work will reveal though, it will be interesting. Have had my 20 month old westie on it for the last two weeks. Went back to vet and they wanted her to go to specialist which she did this week.only wanted to run $2000.00 of allergies testbut vet didnt even put their hands on her.. Didnt think much of it until I watch her over the weekendOMG this baby was having a seizure !!!! FDA approval of APOQUEL is based on results of two clinical trials conducted in the There are a lot of factors to consider when trying to determine which is better for dogs Benadryl or Zyrtec. Noticeably happier and energetic. I thought a noise outside may have scared her, so I gave her belly pats and love until she settled down and went back to sleep. Benadryl is an antihistamine that also works as a mild sedative to help ease anxiety. Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 He is now experiencing tremors all over and weakness/pain in the front legs. Denise. Nothing worked. He was a healthy and playful boy and certainly did not act his age!!! However, his alk phos was literally off the chart and we could not get it down. The vet was sure it was her thyroid and we did all the tests and they came back negative. He still has the runs. My 14 year old Boston Terrier.my best friend in the world had been plagued by itching his entire life. We havent been able to test for what his allergies could be yet, but the vet thinks it could be something environmentalmold, pollen, dust, something. If these sort of dermatologic/parasitic overgrowths occurred in humans from treatment with JK inhibitors, it would certainly prompt the FDA to take action to protect the patient population utilizing these medications from these severe adverse events Probably more concerned with the monthly sale of Apoquel to me rather than reporting this AE. Can you give dogs Benadryl and Apoquel together? This medication is not worth your puppys life. However, when the pollen count starts to rise, so does the risk of our dogs suffering from allergies. Can both be given for an extended car ride this weekend? I do want to note that when he first started on the apoquel, it worked really well. The sedative properties are beneficial in these instances. He had to have the dosage raised today after 2 seizures this morning. I called the vet and he told me to stop the medication and keep a closed eye on him. In simple terms, apoquel changes how the immune system acts. dog? These beneficial bacteria play a role in normalizing the overactive immune system. I called the vet and was informed to Keep her on the Apoquel and give her boiled rice and chicken for her vomiting. I gave her the boiled rice and chicken but I immediately took her off of the Apoquel and her vomiting stopped. Research has found an ingredient known as praline-rich polypeptide (PRP) in bovine colostrum; it appears to be what is helping decrease the allergy symptoms. I hate to have my sweet condfidant puppy be scared of his own shadow but at the same time hes super happy and playful to not be so itchy! I am planning on trying to wean him off the Apoquel as soon as I feel he is stable. (Answered 2023), How Much Food Should My 8 Week Old Puppy Eat? We had started a chemotherapy regimen in November which completely zapped her energy. http://www.dogsnaturallymagazine.com/wouldnt-give-dog-new-allergy-drug/. We went to the vet because she was quite lethargic. Just yesterday his lab panel showed elevated liver enzymes and he was transferred to a 24 hour emergency hospital. My comment would be to not use this unless everything else is exhausted. Brief in length, 5 minutes. Please everyone try Natural pet! She nearly died and has never been the same since. After a few months the vet recommended Apoquel, we never thought to ask about side effects. He has had these issues his whole life (and in the last two years we have moved two hours away). I have an 11 year old pit bull that has had skin allergies for years before our vet put him on Apoquel. Has anyone else has had similar issues? The dose of Apoquel is 0.18 to 0.27mg depending on the body weight of your dog. These drugs were first discovered in the 1930s. My dog was prescribed this medication and quickly developed a serious urinary tract infection. He is 25 lbs (huge westie, I know), and I have found that if I give him 1/4 pill in the morning that the side effects go away and itching is pretty much under control. Of the 247 dogs studied, 26 were removed for unknown reasons and 18 were euthanized. You will need to work closely with your vet to find the treatment regime that works best for your pooch. Is there another page that Im missing. I bathe him weekly and this helps. Upon returning home from work The veterinarian removed the cysts with Aries requiring to stay overnight under observation. Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. That seemed to set him off so gave him a little more for a few days and also ketaconazole. After 3 days we stopped the medication because her organs were shutting down. petrified! He has been on this drug for three years and his allergies are gone. The colostrum dose for dogs with allergies varies based on the company; I advise giving of the human dose per 20lbs daily. I thought we were going to lose him. Zoetis has made a fortune on this drug, it is time to stop the suffering. I cant prove it was the Apoquell but I was never educated on the side effects. My vet put my 2year old French Bulldog on this med last week for constant paw licking as piriton wasnt giving him much relief 1st day my whole family said He was acting odd later that night it seemed like he was seeing & sensing things that werent there on the 2nd day he was becoming a bit nervous & also lifting his back paw like he was in discomfort that night he was like completely spooked! In fact, the other drugs used for this condition carry similarly disturbing side effects. When I took him to the vet, he had 106 degree temp (above 102.5 in dogs is a fever) and they couldnt figure out where the infection was. We had no choice but to euthanize him early this morning. Thank you so much for some holistic suggestions. I am aware that in the pharmaceutical world when a medication becomes FDA approved, the company must conduct as post marketing surveillance program to detect any adverse events or idiosyncratic reactions that occur especially when the medication is being utilized in a much large patient population. It's a synthetic monoclonal antibody . My story started a year ago last august when he scratched his jaw bloody on both sides. You complain about others doing certain things, but you chose to quit. Apoquel seems to be an amazing drug. In February 2017, we had to take Aries back again to the veterinarian since he had have 2 cysts that were getting larger almost weekly. You have to understand one thingPeatie has a laundry list of ailmentsarthritis (all limbs and back, heart murmur (diagnosed at first vet visit), cataracts (90% blind) and close to 100% deaf. What do we do to protect our fur babies? Thanks for sharing and I hope your dog fully recovers! I use duoxo chlorhexadine shampoo as well as the spray. For the past month or so he just wasnt right; lethargic, increased ear infections and two weeks ago while chasing a ball it looked as though a linebacker took the legs out from under him, but only on his right side. I decided to stop the medication. So, our story is our 7 mo. I took her back to the vet in November as I was so concerned about the weight gain. Im anxious to see what happens. Please listen to Dr. Jones. Dogs under one year of age should not take Apoquel. It seems vets are putting dogs on it right and left, and while it may help with those symptoms..new ones develop that can be far worse. She hasnt had a seizure no in 11 months. More serious side effects can include coma and apnea. Ill try it too. I hate that we now must take him off the medicine because he has been able to live a more comfortable life, but I cant ignore the side effects and how its affecting him. August 18, 2020 By //byThe Dogsnet Team 2 Comments. Had my dog on this for about a month. Tried Cytopoint once, with no luck. He also has a nodule on his spleen which will now be getting investigated. It worked almost immediately. One leg even appears lumpy. Assuming you are a veterinarian, you may want to consider being slightly more professional in your communication Instead of taking the heat, paying what you owe for flapping your gums when you said you wouldnt, you took the easy way out. So, it is important that you only give this medication to your dog under your vets supervision. She has NEVER done this, she wont even puke on the floor she runs to her crate she is the most courteous dog when it comes to messing anything up. If Apoquel is responsible for his life threatening illness and the issues other owners have had with their pets, surely we should be doing something to get this drug taken off the market. I am pretty sure her seizures are tied in with a build up of Apoquel but its impossible to be sure. When I looked them up I immediately stopped the drug but it was too late. She is Am. So glad I saw these posts. The answer is: it depends on the weight of your dog. He was going to go back onto Apoquel after being off it for a short time. At this time he had a steroid injection to get him over the intiial itching. Nadya. She cant even find her toys unless I put them in her mouth. I have many questions, and was wondering does anyone who has had similar issues with apoquel know how long this nightmare of a drug stays in a dogs system. I have a 90 pound mixed male Shar pei who has been on Apoquel 3 years now. Both need to go out more often to pee. This is not like him.So I am going to quit giving him this med. She has been on it for over six months now. She sounds like a very sweet dog not making a mess for you. The result was: a depressed dog with increased appetite and it did not help against the itching at all. He is still on hepaticlear..3 years later. Then Vet encouraged us to continue every 2nd day which we did. Never again will I use that drug. I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. My dog is much worse now and has a tumor under her forearm. Stop the medication synthetic monoclonal antibody pretty sure her seizures are tied in with a painful leg! Along with antinausea pills returning home from work the veterinarian removed the cysts with Aries requiring to overnight... Started having side effects and yes, it worked really well choice to... Only give this medication to your fur baby so you have to weight out the benefit vs. the risks stopped... 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