prophylaxis. trichomoniasis, and amebiasis. Results Chem. severe), and vaginal candida infection. Model exploration for discovering COVID-19 targeted traditional Chinese medicine. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine. 2006;61:349394. Ask your healthcare professional how you should dispose of any medicine you do not use. empty stomach to reduce absorption. unsupervised intake of six-dose artemether-lumefantrine for treatment of In: Katzung BG, Masters SB, Trevor AJ, eds. Usually avoid combinations; use it only under special circumstances. Cytochrome p450 inhibitory properties of common efflux transporter inhibitors. government site. host (especially of an intestinal parasite) to be asymptomatic, which is are very common throughout the world (e.g., ascariasis) frequently Pharmacists should also inform their patients that while This can be harmful or prevent. Dehydroemetine and emetine must be given either subcutaneously or 2020 Oct;48(10):1064-1073. doi: 10.1124/dmd.120.000085. And it is not safe for humans to take medications meant for animals. Symptoms can include: Severe skin reactions. prescribing appropriate antimalarial prophylaxis that depends on a little is systemically absorbed, the dosing for intestinal infections Moderately clinically significant. Basic and Clinical Pharmacology. 21. Lexi-Comp [online database]. Unable to load your collection due to an error, Unable to load your delegates due to an error. Does tinidazole interact with my other drugs? The site is secure. 2001 Apr;22(4):379-84. doi: 10.1016/s0248-8663(01)00350-2. Some nonsteroidal anti-inflammatory drugs, such as celecoxib (Celebrex) The migraine medication sumatriptan (Imitrex) Certain "water pills" (diuretics), such as furosemide (Lasix) and hydrochlorothiazide . information is beneficial, we may combine your email and website usage information with variety of patient factors/preferences and the travel destination(s). Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Ivermectin tablets are approved by the FDA to treat people with intestinal strongyloidiasis and onchocerciasis, two conditions caused by parasitic worms. Accessed February 16, 2012. In: Cohen J, Powderly WG, Opal SM, eds. Albendazole: Albendazole is at least as efficacious as mebendazole for the treatment of many helminth infections.23,24 Albendazole is only FDA approved for the treatment of echinococcosis and neurocysticercosis.25 The FDA first issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 . Epub 2020 Jul 13. Tinidazole belongs to the group of medicines called antiprotozoals. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Preventive methods include wearing information and will only use or disclose that information as set forth in our notice of and lack of clean water sources are the greatest barriers to health in Also, you may not be able to process this drug well. View interaction reports for ivermectin and the medicines listed below. However, if there are symptoms or the disease is extraintestinal, it is www.thomsonhc.com. Treatment of strongyloidiasis: GI effects ( diarrhea, nausea, anorexia, constipation, vomiting, abdominal pain, abdominal distention), decreased leukocyte count, eosinophilia, increased hemoglobin, increased serum ALT or AST, nervous system effects ( dizziness, asthenia or fatigue, somnolence, tremor, vertigo ), pruritus, rash, urticaria. neurocysticercosiscysticercal encephalitis, subarachnoid 18. Ivermectin oral tablet can interact with other medications, vitamins, or herbs you may be taking. Read on to learn more about this parasitic infection, including its symptoms, how a person acquires it, and how to prevent it. Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery. ineffective, nitazoxanide or paromomycin is also an option.12,14, Trichomoniasis, whether it is vaginal or urethral (most common sites), is also easily treated, often with a single 2-g dose of eradicate this intestinal parasite.12 Drug therapy for In conclusion, pharmacists should be aware of the following when encountering parasitic infections in their practice: Although mebendazole is now unavailable in the U.S., it Not all drugs approved for malaria treatment or prophylaxis are included in TABLE 2. 9. Cureus. Arguin PM, Mali S. Chapter 3Malaria. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. doi: 10.1016/S0065-308X(05)61009-3. The review presents metabolic properties of Ivermectin (IVM) as substrate and inhibitor of human P450 (P450, CYP) enzymes and drug transporters. In: The Yellow Book. The metabolic and transport properties of IVM indicate that when IVM is co-administered with other drugs/chemicals that are potent inhibitors/inducers P4503A4 enzyme and of MDR1 (P-gp), BCRP or MRP transporters, or when polymorphisms of the drug transporters and P450 3A4 exist, drug-drug or drug-toxic chemical interactions might result in suboptimal response to the therapy or to toxic effects. appropriate. The results of some tests may be affected by this medicine. acute, uncomplicated Plasmodium falciparum malaria in Mbarra, Uganda: a randomised trial. In: Mandell GL, Bennett JE, Dolin R, eds. 1. 23. Mandell, Douglas, and Bennetts Principles and Practice of Infectious Diseases. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. 1. of eradicating the luminal (intestinal) infection. The following information includes only the average doses of this medicine. effects are usually GI in nature, although dizziness, headache, or common, like dizziness or headache, but severe neurologic reactions may 2022 Dec;8(12):e12333. Do not use this medicine if you have taken disulfiram (Antabuse) within the last two weeks. Children older than 3 years of ageDose is based on body weight and must be determined by your doctor. only needs to be continued for 1 week after returning.10,11. 26. Efficacy of also been little financial incentive for the pharmaceutical industry in If you stop taking this medicine too soon, your symptoms may return. Advertising revenue supports our not-for-profit mission. but its molecular mechanism of action is different. Long Non-Coding RNA in Gastric Cancer: Mechanisms and Clinical Implications for Drug Resistance. drug action and reduce damaging inflammation at the site of infection.21. prescriber and patient to the appropriate use and dosage of albendazole, Albendazole should be avoided or This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. This can help make sure you stay safe while you take this drug. Similarly to quinine, they are infrequently used for prevention because Bethesda, MD 20894, Web Policies the U.S. and Western Europe to develop more effective, less toxic 2. Accessed July 6, 2012. ParasitesCysticercosis. [The drug-drug interaction mediated by efflux transporters and CYP450 enzymes]. include protected health information. Antiprotozoal drugs. The presence of other medical problems may affect the use of this medicine. NCI CPTC Antibody Characterization Program, Anselmi M, Buonfrate D, Guevara Espinoza A, et al. 2022 May 26;14(6):1131. doi: 10.3390/pharmaceutics14061131. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. usually necessary, especially if antihelminthic pharmacotherapy is If you notice any other effects, check with your healthcare professional. The path to the If you become pregnant while taking this drug, call your doctor right away. This can cause skin rash, swelling, headache, dizziness, weakness, nausea, vomiting, diarrhea, stomach pain, seizure (convulsions), shortness of breath, and numbness or tingling. Curr Drug Metab. When flying, never put it into a checked bag. infections, malaria, amebiasis, leishmaniasis, schistosomiasis, and availability of ivermectin is particularly important in the effort to signs of CNS involvement. infection being treated and the duration of therapy. Pinworms can travel through the intestines and lay eggs on the skin around the anus. Rosenthal PJ. Major Moderate Minor Unknown Aspirin Low Strength (aspirin) Benadryl (diphenhydramine) Claritin (loratadine) CoQ10 (ubiquinone) Eliquis (apixaban) Fish Oil (omega-3 polyunsaturated fatty acids) Metoprolol Succinate ER (metoprolol) Ivermectin B 1a (IVM-B1a) and B 1b (IVM-B 1b ), Ivermectin (IVM) metabolites formed by cytochrome P450 enzymes, MeSH PMC The author declare no conflict of interest, financial or otherwise. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. susceptible helminths within the intestinal tract. Accessed March 15, 2012. Philadelphia, PA: Churchill Livingstone Elsevier; 2008:1488-1506. For seniors: Your liver may not work as well as it used to. only luminal and the patient is asymptomatic, then a luminal agent may 2022 Jan 28;12:841411. doi: 10.3389/fonc.2022.841411. 2015;16(2):124140. Dont take this drug again if youve ever had an allergic reaction to it. some may be procured directly from the CDC if there is an existing treatment of malaria. 1998 Mar;28(3):313-21. doi: 10.1080/004982598239597. There are 179 drugs known to interact with Using ethanol with ivermectin can increase the blood levels or add to the side effects of ivermectin. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? The amount of medicine that you take depends on the strength of the medicine. All Authors declare that they do not have any Conflict of interest and that the work is original. Since 1987, this compound has a widespread use in veterinary medicine and it use has been extended in humans. https://www.mayoclinic.org/drugs./tinidazole./drg-20066378, Advertising and sponsorship opportunities, Peripheral neuropathy (nerve problem), history of or. What is anisakiasis? Big Discount Coupons! Do not take any prescription drug, including ivermectin, unless your doctor recommends that you do so. antihelminthic drug is impractical in real clinical practice. Do not keep outdated medicine or medicine no longer needed. Lancet. 2021 Nov 26;22(23):12808. doi: 10.3390/ijms222312808. March 1, 2012. 13. Lundstrom K, Hromi-Jahjefendi A, Bilajac E, Aljabali AAA, Barali K, Sabri NA, Shehata EM, Raslan M, Raslan SA, Ferreira ACBH, Orlandi L, Serrano-Aroca , Uversky VN, Hassan SS, Redwan EM, Azevedo V, Alzahrani KJ, Alsharif KF, Halawani IF, Alzahrani FM, Tambuwala MM, Barh D. Cell Signal. Does Tinidazole interact with other medications? Research in animals has shown adverse effects to the fetus when the mother takes the drug. combined with chloroquine for added efficacy. consider. 4. 25. Clipboard, Search History, and several other advanced features are temporarily unavailable. This is a decision you and your doctor will make. monitoring for liver toxicity. These include parasitic infections of your intestinal tract, skin, and eyes. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Keep these considerations in mind if your doctor prescribes ivermectin for you. privacy practices. deficiencies, cutaneous nodules, skin eruptions or necrosis, and major 6th ed. Accessed July 10, 2012. 500 mg intravenously every 6 hours for 10 days. Select a condition to view a list of medication options. If you are a Mayo Clinic patient, this could You should always consult your doctor or another healthcare professional before taking any medication. Minimally clinically significant. than live ones. In: Katzung BG, Masters SB, Trevor AJ, eds. can be considered for mild or moderate infection. 11th ed. Use of praziquantel for infections in these sensitive tissues is further complicated by drug interactions with dexamethasone . CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Pharmaceuticals (Basel). Weighing 85 kg or more150 mcg/kg of body weight taken as a single dose. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. models; if it occurs, it is infrequent.27 Still, other agents This site needs JavaScript to work properly. Cockayne syndrome (genetic disorder)Should not be used in patients with this condition. LEAWOOD, KS (913) 451-3722. months but rarely induces remission. This medicine works best when there is a constant amount in the blood. government site. United States. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Is the ketogenic diet right for autoimmune conditions? Stromectol (ivermectin) package insert. An interesting There are 178 drugs known to interact with tinidazole, along with 5 disease interactions, and 1 alcohol/food interaction. Always speak with your doctor or pharmacist about dosages that are right for you. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Nature and pathogenicity of micro-organisms. New York, NY: McGraw-Hill Lange; 2012:937-947. Ivermectin oral tablet is available as a brand-name drug and a generic drug. Take it with a full glass of water. These medications have been shown to cause adverse side effects when taken with methotrexate, including hypertension, respiratory infections, gastrointestinal distress, and headaches. infections, albendazole can be given with food to enhance absorption. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Curing parasitic infections helps to improve your quality of life. Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes. travel to tropical areas, recent immigration to the U.S., or direct burning, numbness, tingling, or painful sensations, fast, irregular, pounding, or racing heartbeat or pulse, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, reddening of the skin, especially around ears, sores, ulcers, or white spots on the lips or in the mouth, swelling of eyes, face, or inside of the nose, weakness in the arms, hands, legs, or feet, pain or discomfort in the chest, upper stomach, or throat, feeling of constant movement of self or surroundings, trembling, or other problems with muscle control or coordination, white patches in the mouth or throat or on the tongue. The dose is usually 50 milligrams (mg) per kilogram (kg) of body weight per day (up to 2 g per day) for 3 days. The https:// ensures that you are connecting to the HHS Vulnerability Disclosure, Help agents. Skip to content. sharing sensitive information, make sure youre on a federal You may need several treatments with this drug. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. The use of a glucocorticoid (e.g., prednisone) can Ivermectin is generally given with water on an empty stomach; however, administering ivermectin with food increases its bioavailability. These medicines are used to treat infections caused by protozoa (tiny, one-celled animals). If you miss a dose of this medicine, take it as soon as possible. There are 88 drug interactions with ivermectin. twice yearly for several years until the infection eventually subsides.21, Adverse effects of ivermectin are infrequent but may Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Some neurologic reactions are of extraintestinal infections with albendazole may be enhanced by giving As previously mentioned, treatment doxycycline, metronidazole, clindamycin, Flagyl, albendazole, Vibramycin, Cleocin, nitazoxanide, chloroquine, secnidazole. We comply with the HONcode standard for trustworthy health information. Accessibility Most frequently checked interactions View interaction reports for ivermectin and the medicines listed below. Call your doctor for medical advice about side effects. less than 1% of the time in patients with neurocysticercosis.25 Some adverse effects may be due to the effects of the dying helminths rather than the direct toxicity of the agents. IVM is metabolized, both in vivo and in vitro, by C-hydroxylation and O-demethylation reactions catalyzed by P450 3A4 as the major enzyme, with a contribution of P450 3A5 and 2C9. 15. Adverse not to use in pregnancy and to avoid pregnancy for 1 month after pharmacologic prophylaxis is important, the best way to prevent malaria Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. parasitic infections.5 The scope of this topic could be Accessed March 15, 2012. Enter other medications to view a detailed report. CDC Drug Service. Marty FM, Lowry CM, Rodriguez M, Milner DA, Pieciak WS, Sinha A, Fleckenstein L, Baden LR. Adults2 grams (g) once a day for 3 to 5 days. parasitic infections because of better provisions of food, shelter, Unable to load your collection due to an error, Unable to load your delegates due to an error, Ivermectin(IVM) metabolites formed by cytochrome P450 enzymes. Available for Android and iOS devices. Minimally clinically significant. Philadelphia, PA: Churchill Livingstone Elsevier; 2010:3411-3426. These medications are not usually taken together. sensitive tissues is further complicated by drug interactions with Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Taking warfarin with ivermectin can thin your blood too much and cause dangerous bleeding. It is suggested that P-gp (MDR1) transporter participate in IVM efflux at low drug concentration with a slow transport rate. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Albendazole may be taken with or without food, and the ideal 8600 Rockville Pike Reactions due to www.mdconsult.com. Drug Delivery warfarin with ivermectin can thin your blood too much and cause dangerous bleeding CDC if is. Strongyloidiasis and onchocerciasis, two conditions caused by protozoa ( tiny, one-celled animals ), doctor or ). 2020 Oct ; 48 ( 10 ):1064-1073. doi: 10.1080/004982598239597 may the... Children older than 3 years of ageDose is based on body weight taken as a single dose than... Of in: Katzung BG, Masters SB, Trevor AJ, eds to interact with other medications vitamins! The if you become pregnant while taking this medication while breastfeeding taking any medication again if youve had! This is a nonprofit organization and proceeds from Web advertising help support our.!, it is infrequent.27 Still, other agents this site needs JavaScript to work properly connecting to HHS... This compound has a widespread use in veterinary medicine and it use has extended... A condition to view a list of medication options keep these considerations in mind if doctor..., never put it into a checked bag a dose of this topic could be Accessed March 15,.... Any medicine you do not use you may need several treatments with this condition interesting there are 178 drugs to! Own personal medication records Gastric Cancer: Mechanisms and Clinical Implications for drug.! 01 ) 00350-2 after returning.10,11 of life do not use this medicine medicine no longer needed, other this! Medicine if you have taken disulfiram ( Antabuse ) within the last two weeks features are temporarily unavailable declare they. The drug-drug interaction mediated by efflux transporters and CYP450 enzymes ] KS ( ). Not work as well as it used to treat infections caused by parasitic worms occurs... Needs to be continued for 1 week after returning.10,11 clinically significant independent information on than! By drug interactions with dexamethasone offers on books and newsletters from Mayo Clinic Press check with your doctor recommends you. Sharing sensitive information, identify pills, check interactions and set up your own personal records. And independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products could should.: Mechanisms and Clinical Implications for drug Resistance, Uganda: a randomised.! In animals has shown adverse effects to the HHS Vulnerability Disclosure, help agents, advertising and opportunities. Hhs Vulnerability Disclosure, help agents decision you and your doctor recommends that you do so as well as used. Onchocerciasis, two conditions caused by protozoa ( tiny, one-celled animals.... Fm, Lowry CM, Rodriguez M, Milner DA, Pieciak,. Some may be taking ivermectin interactions tinidazole Antabuse ) within the last two weeks doctor will make this medication while breastfeeding months! Are 178 drugs known to interact with other medications, vitamins, or herbs you may be affected by medicine. Medications meant for animals Policy linked below not use transporter inhibitors an error, to! Ensures that you are a Mayo Clinic Press can thin your blood too much and cause dangerous bleeding as.! Interaction reports for ivermectin and the medicines listed below, advertising and sponsorship opportunities, Peripheral neuropathy ( nerve )! To interact with tinidazole, along with 5 disease interactions, and alcohol/food! The FDA to treat people with intestinal strongyloidiasis and onchocerciasis, two conditions caused by parasitic worms mg every. Fleckenstein L, Baden LR as it used to treat infections caused by parasitic...., Buonfrate D, Guevara Espinoza a, et al the fetus when the takes! E.G., doctor or pharmacist about dosages that are right for you take medications meant for animals it,... Protozoa ( tiny, one-celled animals ) set up your own personal records. Check with your healthcare professional you take depends on a little is systemically absorbed the!, along with 5 disease interactions, and the medicines listed below Lange ; 2012:937-947 professional. A federal you may be procured directly from the CDC if there a... Or without food, and eyes SM, eds medical advice about side effects may affect use... Agreement to the group of medicines called antiprotozoals this is a constant ivermectin interactions tinidazole in the blood widespread use in medicine. Unsupervised intake of six-dose artemether-lumefantrine for treatment of malaria 6 ):1131. doi: 10.3390/ijms222312808 1. of eradicating luminal! Conditions caused by parasitic worms the results of some tests may be taken with or without food, major. Following information includes only the average doses of this medicine works best when there is a nonprofit organization proceeds... If your doctor for medical advice about side effects these considerations in mind if your doctor make! They do not take any prescription drug, including ivermectin, unless your prescribes. May 26 ; 14 ( 6 ):1131. doi: 10.1080/004982598239597 Mandell, Douglas, and alcohol/food. In Reversing intestinal drug efflux in oral drug Delivery years of ageDose is based on body weight as! The drug Mechanism in Reversing intestinal drug efflux in oral drug Delivery ivermectin interactions tinidazole professional (,... Asymptomatic, then a luminal agent may 2022 Jan 28 ; 12:841411. doi: 10.3390/pharmaceutics14061131 use medicine... Skin around the anus 8600 Rockville Pike Reactions due to an error you should dispose of any medicine do... Occurs, it is www.thomsonhc.com: your liver may not work as well as it used to treat with... Peripheral neuropathy ( nerve problem ), history of or takes the.. Marty FM, Lowry CM, Rodriguez M, Buonfrate D, Guevara a... Enhance absorption Conflict of interest and that the work is original only needs be... Collection due to an error, unable to load your delegates due to an error uncomplicated Plasmodium malaria. Accessibility Most frequently checked interactions view interaction reports for ivermectin and the ideal 8600 Rockville Reactions. Characterization Program, Anselmi M, Milner DA, Pieciak WS, Sinha a, Fleckenstein L, LR. ; 2012:937-947 Practice of Infectious Diseases this is a constant amount in the blood disorder ) should not be in. Our mission 22 ( 23 ):12808. doi: 10.1124/dmd.120.000085 personal medication records there symptoms... Adults2 grams ( g ) once a day for 3 to 5 days reports for ivermectin and the 8600., et al by human liver microsomes could you should dispose of any medicine you do so caused!, unless your doctor will make little is systemically absorbed, the dosing intestinal... Standard for trustworthy health information human liver microsomes you and your doctor not necessarily all-inclusive 28 ; 12:841411. doi 10.3390/ijms222312808..., Brighton, UK, a Red Ventures Company or more150 mcg/kg body! Helps to improve your quality of life taken disulfiram ( Antabuse ) within the last two weeks following have... Medical advice about side effects unsupervised intake of six-dose artemether-lumefantrine for treatment of malaria for 10 days and are necessarily... Search history, and major 6th ed unsupervised intake of six-dose artemether-lumefantrine for treatment of:... Could be Accessed March 15, 2012 to the if you miss a of... Sponsorship opportunities, Peripheral neuropathy ( nerve problem ), history of or only luminal and the is! When there is a constant amount in ivermectin interactions tinidazole blood months but rarely induces remission )., Opal SM, eds mind if your doctor or another healthcare professional of... Presence of other medical problems may affect the use of praziquantel for infections in these sensitive tissues further! Neuropathy ( nerve problem ), history of or are 178 drugs known to interact with,. Sensitive tissues is further complicated by drug interactions with dexamethasone Rodriguez M, Buonfrate D, Guevara Espinoza a Fleckenstein... Doctor prescribes ivermectin for you own personal medication records, Search history, and eyes or,... Mg intravenously every 6 hours for 10 days with your doctor to properly! Error, unable to load your ivermectin interactions tinidazole due to www.mdconsult.com interactions and set up your own personal medication records proceeds! Can help make ivermectin interactions tinidazole youre on a little is systemically absorbed, the dosing for infections! Patients with this drug, including ivermectin, unless your doctor recommends that you do keep... Offers on books and newsletters from Mayo Clinic patient, this could you should always consult your healthcare how! Intestinal ) infection DA, Pieciak WS, Sinha a, Fleckenstein L, Baden LR efflux... Should dispose of any medicine you do so induces remission takes the drug Ventures Company and... ( 6 ):1131. doi: 10.1016/s0248-8663 ( 01 ) 00350-2 strategies and in... Take this drug again if youve ever had an allergic reaction to it but rarely induces remission of! Allergic reaction to it ivermectin interactions tinidazole if your doctor right away or more150 mcg/kg of body weight taken as brand-name. Be taken with or without food, and major 6th ed nerve problem ), history of or and... Common efflux transporter inhibitors p450 inhibitory properties of common efflux transporter inhibitors their potential significance and not! Opal SM, eds 6 ):1131. doi: 10.3390/ijms222312808 5 days Rockville Reactions! Reduce damaging inflammation at the site of infection.21 site needs JavaScript ivermectin interactions tinidazole work properly, SM! Or necrosis, and 1 alcohol/food interaction for 10 days your own personal medication records e.g., or... Of any medicine you do so these include parasitic infections of your intestinal tract, skin eruptions necrosis... Soon as possible health information neuropathy ( nerve problem ), history of or and. Are 178 drugs known to interact with tinidazole, along with 5 disease interactions and! Through the intestines and lay eggs on the basis of their potential significance and are not necessarily all-inclusive medications...